Ερευνητικές δημοσιεύσεις
Εκτός από την παροχή υπηρεσιών υγείας στους καρκινοπαθείς, στόχος του Εθνικού Δικτύου Ιατρικής Ακριβείας στην Ογκολογία (ΕΔΙΑΟ) είναι και η προώθηση της έρευνας για τον καρκίνο στην Ελλάδα. Ήδη, μέσα στα 3 πρώτα χρόνια λειτουργίας του, το ΕΔΙΑΟ έχει δημοσιεύσει περισσότερα από 10 άρθρα σε έγκριτα επιστημονικά περιοδικά και συνέδρια με κρίση.
T Cells in Chronic Lymphocytic Leukemia: A Two-Edged Sword
Vlachonikola E, Stamatopoulos K, Chatzidimitriou A.
Front. Immunol. 2021 Jan 20;11:612244.
(doi: 10.3389/fimmu.2020.612244)
T-Cell Dynamics in Chronic Lymphocytic Leukemia under Different Treatment Modalities
Vardi A, Vlachonikola E, Papazoglou D, Psomopoulos F, Kotta K, Ioannou N, Galigalidou C, Gemenetzi K, Pasentsis K, Kotouza M, Koravou E, Scarfó L, Iskas M, Stavroyianni N, Ghia P, Anagnostopoulos A, Kouvatsi A, Ramsay AG, Stamatopoulos K, Chatzidimitriou A.
Clin. Cancer Res. 2020 Sep 15;26(18):4958-4969.
(doi: 10.1158/1078-0432.CCR-19-3827)
TRIP – T cell receptor/immunoglobulin profiler
Kotouza MT, Gemenetzi K, Galigalidou C, Vlachonikola E, Pechlivanis N, Agathangelidis A, Sandaltzopoulos R, Mitkas PA, Stamatopoulos K, Chatzidimitriou A, Psomopoulos FE; Hellenic Precision Medicine Network in Oncology.
BMC Bioinformatics 2020 Sep 29;21(1):422.
(doi: 10.1186/s12859-020-03669-1)
Higher-order immunoglobulin repertoire restrictions in CLL: the illustrative case of stereotyped subsets 2 and 169
Gemenetzi K, Psomopoulos F, Carriles AA, Gounari M, Minici C, Plevova K, Sutton LA, Tsagiopoulou M, Baliakas P, Pasentsis K, Anagnostopoulos A, Sandaltzopoulos R, Rosenquist R, Davi F, Pospisilova S, Ghia P, Stamatopoulos K, Degano M, Chatzidimitriou A.
Blood 2021 Apr 8;137(14):1895-1904.
(doi: 10.1182/blood.2020005216)
Higher-order connections between stereotyped subsets: implications for improved patient classification in CLL
Agathangelidis A, Chatzidimitriou A, Gemenetzi K, Giudicelli V, Karypidou M, Plevova K, Davis Z, Yan XJ, Jeromin S, Schneider C, Pedersen LB, Tschumper RC, Sutton LA, Baliakas P, Scarfò L, van Gastel EJ, Armand M, Tausch E, Biderman B, Baer C, Bagnara D, Navarro A, Langlois de Septenville A, Guido V, Mitterbauer-Hohendanner G, Dimovski A, Brieghel C, Lawless S, Meggendorfer M, Brazdilova K, Ritgen M, Facco M, Tresoldi C, Visentin A, Patriarca A, Catherwood M, Bonello L, Sudarikov A, Vanura K, Roumelioti M, Skuhrova Francova H, Moysiadis T, Veronese S, Giannopoulos K, Mansouri L, Karan-Djurasevic T, Sandaltzopoulos R, Bödör C, Fais F, Kater A, Panovska I, Rossi D, Alshemmari S, Panagiotidis P, Costeas P, Espinet B, Antic D, Foroni L, Montillo M, Trentin L, Stavroyianni N, Gaidano G, Francia di Celle P, Niemann C, Campo E, Anagnostopoulos A, Pott C, Fischer K, Hallek M, Oscier D, Stilgenbauer S, Haferlach C, Jelinek D, Chiorazzi N, Pospisilova S, Lefranc MP, Kossida S, Langerak AW, Belessi C, Davi F, Rosenquist R, Ghia P, Stamatopoulos K.
Blood 2021 Mar 11;137(10):1365-1376.
(doi: 10.1182/blood.2020007039)
Primary vitreoretinal lymphomas display a remarkably restricted immunoglobulin gene repertoire
Belhouachi N, Xochelli A, Boudjoghra M, Lesty C, Cassoux N, Fardeau C, Tran THC, Choquet S, Sarker B, Houillier C, Alentorn A, LeHoang P, Soussain C, Touitou V, Merle-Beral H, Hoang-Xuan K, Bodaghi B, Stamatopoulos K, Davi F.
Blood Adv. 2020 Apr 14;4(7):1357-1366.
(doi: 10.1182/bloodadvances.2019000980)
Comparative analysis of targeted next-generation sequencing panels for the detection of gene mutations in chronic lymphocytic leukemia: an ERIC multi-center study
Sutton LA, Ljungström V, Enjuanes A, Cortese D, Skaftason A, Tausch E, Stano Kozubik K, Nadeu F, Armand M, Malcikova J, Pandzic T, Forster J, Davis Z, Oscier D, Rossi D, Ghia P, Strefford JC, Pospisilova S, Stilgenbauer S, Davi F, Campo E, Stamatopoulos K, Rosenquist R, On Behalf Of The European Research Initiative On Cll Eric.
Haematologica 2021 Mar 1;106(3):682-691.
(doi: 10.3324/haematol.2019.234716)
Immunoglobulin gene analysis in chronic lymphocytic leukemia in the era of next generation sequencing
Davi F, Langerak AW, de Septenville AL, Kolijn PM, Hengeveld PJ, Chatzidimitriou A, Bonfiglio S, Sutton LA, Rosenquist R, Ghia P, Stamatopoulos K; ERIC, the European Research Initiative on CLL, and the EuroClonality-NGS Working Group.
Leukemia 2020 Oct;34(10):2545-2551.
(doi: 10.1038/s41375-020-0923-9)
Cytogenetic complexity in chronic lymphocytic leukemia: definitions, associations, and clinical impact
Baliakas P, Jeromin S, Iskas M, Puiggros A, Plevova K, Nguyen-Khac F, Davis Z, Rigolin GM, Visentin A, Xochelli A, Delgado J, Baran-Marszak F, Stalika E, Abrisqueta P, Durechova K, Papaioannou G, Eclache V, Dimou M, Iliakis T, Collado R, Doubek M, Calasanz MJ, Ruiz-Xiville N, Moreno C, Jarosova M, Leeksma AC, Panayiotidis P, Podgornik H, Cymbalista F, Anagnostopoulos A, Trentin L, Stavroyianni N, Davi F, Ghia P, Kater AP, Cuneo A, Pospisilova S, Espinet B, Athanasiadou A, Oscier D, Haferlach C, Stamatopoulos K; ERIC, the European Research Initiative on CLL.
Blood 2019 Mar 14;133(11):1205-1216.
(doi: 10.1182/blood-2018-09-873083)
The B cell receptor in marginal zone lymphoma ontogeny and evolution
Zaragoza-Infante L, Agathangelidis A, Papaioannou M, Chatzidimitriou A, Stamatopoulos K
Ann. Lymphoma 2020
(doi: 10.21037/aol-20-18)
Distinctive signaling profiles with distinct biological and clinical implications in aggressive CLL subsets with stereotyped B cell receptor immunoglobulin
Gerousi M, Laidou S, Gemenetzi K, Stamatopoulos K, Chatzidimitriou A
Frontiers in Oncology
A Cloud-Native NGS Data Processing and Annotation Platform
Mouchakis G, Kostopoulos C, Konstantopoulos S, Kanellos I, Tzerefos A), Vergoulis T and Dalamagas T
In Proceedings of the 7th International Workshop on Data Management and Analytics for Medicine and Healthcare (in conjuction with the 47th International Conference on Very Large Data Bases), 2021.
RAS and BRAF in the foreground for Non-Small Cell Lung Cancer and Colorectal Cancer: similarities and main differences for prognosis and therapies
Critical Reviews in Oncology / Hematology. 2020; 146, 102859
(https://doi.org/10.1016/j.critrevonc.2019.102859)
Incidence and prognosis of clonal hematopoiesis in patients with chronic idiopathic neutropenia
Tsaknakis G, Gallì A, Papadakis S, Kanellou P, Elena C, Todisco G, Bono E, Rizzo E, Molteni E, Fragiadaki I, Mavroudi I, Pontikoglou C, Batas A, Maxouri S, Linardaki E, Tavernarakis N, Malcovati L, Papadaki HA.
Blood. 2021 Oct 7;138(14):1249-1257.
(https://doi.org/10.1182/blood.2021010815)